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Early diagnosis and prophylactic treatment is of the utmost importance to improve prognosis of polyposis patients. The effect of systematic and regular screening of family members at risk for FAP has been proved by the considerable difference in the incidence of colorectal cancer between patients diagnosed due to screening of at-risk family members (5%) compared to patients identified incidentally due to intestinal symptoms (about 60%). Furthermore, a significant improvement in the survival of FAP patients has been noticed as a consequence of the establishment of a central register, responsible for the coordination of screening programmes and information about the disease.

Guidelines for screening and follow-up of FAP-patients and at-risk relatives for FAP, can be downloaded here.